Adjunct Associate Professor
B.S. Southeastern Louisiana University
M.S. University of Southwestern Louisiana
Ph.D. University of Illinois
Research Interests
Thalidomide has been used since 1964 to successfully treat a painful complication of leprosy know as erythema nodosum leprosum (ENL). Its mechanism of arresting ENL, as well as the cause of ENL, are not known. My main interest is to elucidate the cause(s) of ENL as well as mechanism of action of thalidomide in arresting ENL.
Selected Publications
Shannon, E. J., Sandoval F., Krahenbuhl, J.L.: Hydrolysis of thalidomide abrogates its ability to enhance the synthesis of IL-2 as well as its
ability to suppress TNF-alpha. Immunopharmacology 36:5-19, 1997.
Aseffa, A., Dietrich M., Shannon, E. J. Thalidomide does not affect apoptosis of lymphoid cells. Immunopharmacology and Immunotoxicology
19(3):1997.
Shannon, E. J. Pankey, G. Aseffa, A., Sandoval, F., Lutz, B. Thalidomide's ability to enhance IL-2 in HIV-infected individuals is
associated with the percent CD4+ cells in blood. Immunopharmacology. In press 1999.
Shannon, E. J. Thalidomide-Will the Past Overshadow a Promising Future? 24th Kellersberger Memorial Address to the Ethiopian Medical Society.
Journal of the Ethiopian Medical Society. In press 1999.
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