Venugopal, Changaram  S.
Professor of Veterinary Pharmacology
Department of Veterinary Clinical Sciences  (8/28/1981)
Airway and Vascular Pharmacologist  
B.V.Sc., Kerala University (India), 1963
M.Sc., Calicut University (India), 1971
M.S., Massachusetts College of Pharmacy and Applied Health Science, 1975
Ph.D., Massachusetts College of Pharmacy and Applied Health Science, 1980
Email cvenugopal@vetmed.lsu.edu http://LSUequine.com
Departmental Phone 225-578-9748
Clinical Service
Clinical Interests Recurrent airway obstruction in horses
Research Interests Inflammatory mediators in airway hyperreactivity
Biographic Sketch

Positions held

Senior Research Associate, Harvard University, Harvard.Med.Sch. 1976-80
Postdoctoral fellow, Harvard University, Harvard Med. Sch., 1980-81
Assistant Professor of Pharmacology, LSU-SVM, Dept. VPT, 1981-85
Associate Professor of Pharmacology, LSU-SVM, Dept. VPT, 1985-91
Professor of Pharmacology, LSU-SVM, Dept. VPT, now CBS, 1991-2003
Professor of Pharmacology, LSU-SVM, Dept. VCS, 2003-Present

Personal Interests and Skills

Shotokan Style Karate
Shuttle Badminton
Travel

Selected Refereed Publications

Venugopal, CS, Moore RM, Holmes EP, Koch CE, Seahorn, TL, Beadle, RE. Comparative responses of bronchaila rings to mediators of airway hyperreactivity in clinically healthy horses and those affected with summer pasture-associated obstructive pulmonary disease. Am. J. Vet Res., 62 (2): 259-263, 2001.

Venugopal, CS, Holmes, EP, Koch CE, Curtis, LA, Holm, AS, Moore, RM. In vitro pharmacological evaluation of two endothelin-1 antagonists on equine colonic vessel rings. Am J Vet Res., 62 (2): 154-159, 2001.

Tetens, J, Venugopal, CS, Holmes EP, Koch CE, Hosgood G., Moore, RM. In vitro relaxation of equine colonic arterial and venous rings to adenosine triphosphate. Am J Vet Res., 62(12): 1928-33, 2001.

Ramaswamy, CM, Eades SC, Venugopal CS, Hosgood, G, Garza Jr. F., Barker SA, Moore, RM. Plasma endothelin concentrations of endothelin-like immunoreactivity in healthy horses and horses with naturally acquired gastrointestinal tract disorders. Am. J. Vet. Res., 63(3): 454-458, 2002.

Krishnakumar S, Holmes, EP, Moore, RM, Kappel, L, Venugopal CS. Nonadrenergic noncholinergic excitatory innervation in asthma: Role of neurokinin-2 receptors. J. Auton & Autacoid Pharmacology, 22: 1-11, 2002.

Pinto CRF, Paccamonti DL, Eilts BE, Venugopal CS, Short CR, Gentry LR, Thompson Jr. DL, Godke, RA. Concentrations of nitric oxide in equine preovulatory follicles before and after administration of human chorionic gonadotropin. Theriogenology 60: 819-827, 2003.

Venugopal, CS, Christopher, C., Wilson, S., Polikepahad S., Deaqueant, E., Holmes, EP. Pharmacological evaluation of NK-2 receptor antagonists on guinea pig airways. Am. J. Vet Res., 65(7): 984-991, 2004.

Walesby, HA. Venugopal, CS, Hosgood, G., Eades, SC., Moore, RM. In vitro evaluation of contractile response of the equine circular and longitudinal myometrium of the non-gravid uterine horn to endothelin-1. Am J Vet Res., 66(6): 1094-1100, 2005.

Moore, RM., Sedrish, SA, Holmes, EP, Koch CE, Venugopal CS. Role of endothelium and nitric oxide in modulating in vitro responses of colonic arterial and venous rings to vasodilatory neuropeptides in horses. Can J. Vet Res., 69(2): 166-122, 2005.

Ramaswamy CM, Eades, SC, Moore RM, Hosgood G, Venugopal CS. Characterization of in vitro responses of equine cecal longitudinal smooth muscle to endothelin-1. Am J Vet Res., 66(7): 1202-08, 2005.

Doi AM., Lou, Z, Holmes EP, Venugopal CS, Nyagode B. James, MO, Kleinow KM. Intestinal bioavailability and biotransformation of 3, 3’, 4, 4’-tetrachlorobiphenyl (CB 77) in in situ preparations of channel catfish following dietary induction of CYPIA. Aquatic Toxicology, 77(1): 33-42, 2006.

Polikepahad, S., Paulsen DB, Moore, RM, Costa LRR, Venugopal CS. Immunohistochemical determination of expression of endothelin receptors in bronchial smooth muscle and epithelium of healthy horses and horses affected by summer pasture-associated obstructive pulmonary disease. Am J. Vet. Res., 67(2): 348-357, 2006.

Venugopal, CS, Polikepahad, S, Holmes, EP, Vanden Heuvel J, Leas TL, Moore, RM. Endothelin receptor alterations in equine airway hyperreactivity, Can J Vet Res., 70: 50-57, 2006.

Stokes AM., Venugopal, CS, Hosgood, G., Eades, SC., Moore, RM. Comparison of two endothelin antagonists on in vitro responses of equine palmar digital arterial and venous rings to endothelin-1. Can J. Vet. Res., 70(3): 197-205, 2006.

Polikepahad, S., Moore, RM and Venugopal, CS. Endothelins and airways – A short review. Res Commun. In Mol Pathol & Pharmacol, 119: 1-51, 2006

Polikepahad, S., Haque, M., Francis, J., Moore, RM, Venugopal, CS. Characterization of pulmonary endothelin receptors in healthy and summer pasture-associated obstructive pulmonary disease (SPAOPD)-affected horses. Can J Vet Res., 74 (4): 340-349, 2008.


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