Lopez, Mandi  J.
	Assistant Professor of Veterinary Surgery Department of Veterinary Clinical Sciences  (1/16/2004)
	Orthopedic Research Scientist
	Director, Laboratory for Equine and Comparative Orthopedic Research, Equine Health Studies Program
	B.S., Humboldt State University, 1988 D.V.M., University of California, Davis, 1993 M.S., University of Wisconsin, 1997 Ph.D., University of Wisconsin, 2001
	Diplomate, American College of Veterinary Surgeons

Email	mlopez@vetmed.lsu.edu		http://equine.vetmed.lsu.edu/lecor.html
Departmental Phone	225-578-9500
Clinical Service	Adult Stem Cell Service
Clinical Interests	Orthopedics
Research Interests	Design and implementation of surgical implants and devices, biomechanical testing, motion analysis, hip dysplasia, cranial cruciate ligament disease, suspensory ligament desmitis, and ostoearthritis.
Biographic Sketch Dr. Lopez received her DVM from the University of California-Davis before completing an agricultural practice internship at Kansas State University and a combined Large Animal Surgery and Master’s degree at the University of Wisconsin-Madison. With National Institutes of Health funding, she then completed a Ph.D. in applied biomechanics at the University of Wisconsin followed by an NIH-supported post-doctoral fellowship in applied biomechanics for the study of osteoarthritis also at the University of Wisconsin. Dr. Lopez joined the VCS faculty in 2004 to design, equip, and implement a comparative, translational program for the advancement of orthopedic science. The program is made possible by funding by the Governor’s Biotechnology Initiative and the LSU Board of Regents. Work within the program has been funded by the National Institutes of Health, the American Kennel Club Health Foundation, the American College of Veterinary Surgeons Foundation, the Equine Health Studies Program, the Veterinary Clinical Sciences Department, the School of Veterinary Medicine and the Collie Health Foundation. Associate Editor for Invited Reviews and Themed Issues, Veterinary Surgery Book Chapters Markel MD, Lopez MJ. Chapter 81 - Bone Biology and Fracture Healing, in Auer JA and Stick JA (eds): Equine Surgery, 3rd ed. St. Louis, MO, Elsevier Science, 2005, pp 991-1000. Lopez MJ, Edwards RB III, Markel MD. Healing of Normal and Osteoporotic Bone, in An YH (ed): Orthopaedic Issues in Osteoporosis. New York, NY, CRC Press, 2002, pp 55-70. Edwards RB, Lopez MJ, Markel MD. Histologic Analysis of Bone Healing. In: YH An, KL Martin (eds): Handbook of Histologic Methods for Bone and Cartilage. Totowa, New Jersey, Humana Press, 2001, pp 375-389. Lopez MJ, Markel MD. Bending Tests of Bone, in An YH and Draughn RA (eds): Mechanical Testing of Bone and the Bone-Implant Interface. New York, NY, CRC Press, 2000, pp 207-217. Selected Publications Lopez MJ, McIntosh KR, Spencer ND, Borneman JN, Horswell R, Anderson P, Yu G, Gaschen L, Gimble JM. Acceleration of Spinal Fusion Using Syngeneic and Allogeneic Adult Adipose Derived Stem Cells in a Rat Model. J Orthop Res e-pub ahead of print Schaefer SL, Lu Y, Seeherman H, Li XJ, Lopez MJ, Markel, MD. The effect of rhBMP-2 on tibial plateau fractures in a canine model. J Orthop Res e-pub ahead of print Vasanjee SC, Paulsen D, Hosgood G, Robinson SO, Lopez MJ. Characterization of normal anterior cruciate ligament associated synoviocytes. J Orthop Res 26(6):809-15, 2008. Lauer SK, Hosgood G, Ramirez S, Lopez M. In vivo comparison of two hinged transarticular external skeletal fixators for multiple ligamentous injuries of the canine stifle. Vet Comp Ortho Traumatol 21:25-35, 2008. Lopez MJ, Lewis B, Swaab M, Markel MD. Relationships among measurements obtained by use of computed tomography and radiography and scores of cartilage microdamage in hip joints with moderate to severe joint laxity of adult dogs. Am J Vet Res 69:362-370, 2008. Vidal MA, Kilroy GE, Lopez MJ, Johnson JR, Moore RM, Gimble JM. Characterization of equine adipose tissue–derived stromal cells: Adipogenic and osteogenic capacity and comparison to bone marrow-derived mesenchymal stromal cells. Vet Surg 36: 613-622, 2007. Selected Grant Support Lopez MJ, Gimble JM, Wise G, Nelson S, Yoshimura M. Adult Stem Cell Suppression due to Alcohol Induced Microenvironment Alterations. NIH-NIAAA, $220,000 (2008- 2010) Gimble J, Lopez MJ, Bubenik L, Lauer S, Gordon S, McIntosh K, Smith A. Spinal Fusion Using Adipose Derived Adult Stem Cells, Small Business Technology Transfer Program, NIH-NIAMS (Co-PI), $100,000. (2006-2007) Lopez MJ. Prevention of hip dysplasia with thermal energy. Mentored Research Scientist Award (K01). NIH-NIAMS Grant # 1 K01 AR02174-01 (P.I.) $584,922. (2001-2007) Lopez MJ, Markel MD. Coxofemoral joint modification to prevent hip dysplasia. Individual National Research Service Award, NIH-NIAMS Grant #1 F32 ARO8523-01 (P.I.) $106,632. (1998-2001)
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