The Analytical Systems Laboratories
are central service, comprehensive analytical laboratories, consisting
of the Laboratory for Drug Residue Studies, the Equine Medication
Surveillance Laboratory and the Analytical Systems Laboratory.
The Laboratory for Drug Residue Studies was established in 1991 and
provides instrumentation and expertise for the performance of drug
and biological molecule pharmacokinetics, metabolism, tissue distribution
and analytical method development. The laboratory is also equipped
to conduct complete drug profiling using radiolabeled test materials.
These laboratories operate under Federal Good Laboratory Practices
regulations and have generated data for the Food and Drug Administration
(FDA) and private industry for submission for veterinary drug approvals
by U.S. and foreign regulatory agencies.
The Equine Medication Surveillance Laboratory was established in 1987
and has served as the official laboratory for the Louisiana State
Racing Commission since that time. The laboratory screens over 10,000
urine and blood samples per year and has developed sophisticated methodology
for detection and confirmation of drugs and their metabolites. The
laboratory also conducts illegal drug-use testing for the LSU Department
of Athletics and serves as a source of information to the racing industry
and the public regarding drug pharmacology, metabolism and clearance.
The Analytical Systems Laboratory, established in 1985, houses advanced
mass spectrometry and other analytical equipment that is used to support
other laboratories as well as the research of SVM faculty and graduate
students. Equipment in these laboratories includes a Micromass Quattro
II GC/LC/MS/MS (+/-) with ApcI and ESP interfaces, one HP 1090 II,
low-flow HPLC (1 ul/min), three 1090 HPLCs equipped with UV-diode
array, fluorescence, electrochemical and radio-monitor detectors,
a HP 5973 GC/MS system and beta and gamma counters for radiolabel
analyses. The laboratory is currently developing full capabilities
to conduct low- and high-throughput proteomics analysis and is enhancing
its abilities to conduct small and large scale protein purification.
Contact: Dr. Steven Barker, Director, 225-578-3602
