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Education
D.V.M. Kitasato University, Japan
• Ph.D. University of Georgia
•
Post-doctoral fellow at National Institute of
Environmental Health Sciences, NIH
•
Diplomate, American College of Veterinary
Pathologists
Research Interests
Dr. Wakamatsu’s primary research interest is in pathogenesis of viral
and other infectious diseases.
Selected Publications
Iyer AV, Boudreaux M, Wakamatsu N, Roy AF, Baghian A, Chouljenko
VN, Kousoulas KG. Complete genome analysis and virulence characteristics
of the Louisiana West Nile virus strain LSU AR01. Virus Genes
38:204-214, 2009.
Iyer A, Pahar B, Boudreaux M, Wakamatsu N, Roy A, Chouljenko V,
Baghian A, Apetrei C, Marx P, Kousoulas KG. Recombinant vesicular stomatitis
virus-based West Nile vaccine elicits strong humoral and cellular immune
responses and protects mice against lethal challenge with the virulent West
Nile virus strain LSU-AR01. Vaccine 27:893-903, 2009.
Koujitani T, Ton TT, Lahousse SA, Hong HL, Wakamatsu N, Sills R. K-ras
cancer gene mutations in lung tumors from female Swiss (CD-1) mice exposed
transplacentally to 3’-azido-3’deoxythymidine. Environmental and
Molecular Mutagenesis 49:720-726, 2008.
Wakamatsu N, Collins JB, Parker JS, Tessema M, Clayton NP, Ton TT, Hong
HL, Belinsky S, Devereux TR, Sills RC, Lahousse SA. Gene expression studies
demonstrate that the K-ras/Erk MAP kinase signal transduction pathway and
other novel pathways contribute to the pathogenesis of cumen-induced lung
tumors. Toxicologic Pathology, 36:743-752, 2008.
Hong HL, Ton TT, Kim Y, Wakamatsu N, Clayton NP, Chan PC, Sills RC,
Lahousse SA. Genetic alterations in K-ras and p53 cancer genes in lung
neoplasms form B6C3F1 mice exposed to cumene. Toxicologic Pathology,
36:720-726, 2008.
Wakamatsu N,
King DJ, Seal BS, Brown CC. Detection
of Newcastle disease virus RNA by reverse transcription-polymerase chain
reaction using formalin-fixed, paraffin-embedded tissue and comparison with
immunohistochemistry and in situ hybridization.
Journal of Veterinary Diagnostic
Investigation, 19(4):396-400, 2007.
Wakamatsu N,
Hong HL, Devereux TR, Sills RC. Overview of the molecular carcinogenesis of
mouse lung tumor models of human lung cancer.
Toxicologic Pathology,
35(1):75-80, 2007.
Wakamatsu N,
Surdyk K, Carmichael KP, Brown CA. Histologic and ultrastructural studies of
juvenile onset renal disease in four Rottweiler dogs.
Veterinary Pathology, 44(1):
96-100, 2007.
Wakamatsu N,
King DJ, Seal BS, Peeters BPH, Brown CC. The effect on pathogenesis of
Newcastle disease virus LaSota strain from a mutation of the fusion cleavage
site to a virulent sequence. Avian
Diseases, 50(4):483-488, 2006.
Wakamatsu N,
King DJ, Seal BS, Kapczynski DR, Brown CC. Experimental pathogenesis for
chickens, turkeys, and pigeons of exotic Newcastle disease virus from an
outbreak in California during 2002-2003.
Veterinary Pathology, 43(6):
925-933, 2006.
Wakamatsu N,
King DJ, Seal BS, Samal SK, Brown CC. The pathogenesis of Newcastle disease:
A comparison of selected Newcastle disease virus wild-type strains and their
infectious clones. Virology,
353(2): 333-343, 2006.
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