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Timothy W. Morgan
Assistant Professor, Pathology
Laboratory:
Phone: 225-578-9737
Fax:
225-578-9701
tmorgan@vetmed.lsu.edu
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Education:
Research Interests
Dr. Morgan is interested in the host inflammatory response to E. coli
O157:H7 infection, and the role of the host inflammatory response in the
movement of Shiga toxin, produced by E. coli O157:H7, from the
intestinal lumen to the systemic circulation. To investigate this
response, Dr. Morgan has developed a neonatal pig model of E. coli
O157:H7 infection and systemic Shiga toxin-induced damage. By
understanding the role of the host inflammatory reaction in mucosal
barrier changes that may lead to Shiga toxin translocation, it may be
possible to develop preventative measures or treatment protocols to
reduce or eliminate the translocation of Shiga toxin and thus prevent
the development of Hemolytic Uremic Syndrome, which is the leading cause
of acute renal failure in children in the United States.
Selected Publications
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