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Maria Antonieta Guerrero-Plata
Assistant Professor
Laboratory:
Phone: 225-578-9678
Fax:
225-578-9701
aguerrp@lsu.edu
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Education:
B.S. Universidad Autónoma de Tamaulipas at Reynosa, Mexico • M.S.
Universidad Nacional Autónoma de México • Visiting student at Imperial
College of Science, London, U.K. • Ph.D. Universidad Nacional Autónoma
de México •
Postdoctoral Fellow University of Texas Medical Branch at Galveston
Positions:
2006 – 2007
Instructor, Department of Pediatrics, University of Texas Medical Branch at
Galveston, Tex.
2007 – 2009
Assistant Professor, Department of Pediatrics, University of Texas Medical
Branch at Galveston, Tex.
2009 – present
Assistant Professor, Department of Pathobiological Sciences, Louisiana State
University School of Veterinary Medicine, Baton Rouge, La.
Research Interests:
Dr. Guerrero-Plata’s
research interests are in the field of viral immunology focused on innate
immunity, dendritic cells and respiratory viruses. Her work includes the
study of the immune response to respiratory
syncytial virus and human metapneumovirus, the most important cause of lower
respiratory tract infections in children, elderly and immunocompromised
patients. The long-term goal of her research is to develop new strategies to
boost antiviral immunity and long-lasting protection against respiratory
viral pathogens that cause significant airway morbidity. Additional studies
in her laboratory are directed to determine the mechanisms by which
environmental factors alter the frequency and
severity of respiratory viral infections.
Selected Publications:
Guerrero-Plata A.*,
D. Kolli, C. Hong, A. Casola and R. P. Garofalo.
(2009). Subversion of Pulmonary Dendritic Cell Function by Paramyxovirus
Infections. J. Immunol. 182:3072-3083. (*Corresponding Author).
Castro S., D. Kolli, A. Guerrero-Plata, R. P. Garofalo and A.
Casola.
(2008). Cigarette Smoke Condensate Enhances Respiratory Syncytial
Virus-induced Chemokine Release by Modulating NF-kappa B and Interferon
Regulatory Factor Activation. Toxic Sci. 106: 509-518.
Kolli D., E.L. Bataki, L. Spetch, A. Guerrero-Plata, A.M. Jewell,
P.A. Piedra, G.N. Milligan, R.P. Garofalo and A. Casola. (2008). T
Lymphocytes Contribute to Antiviral Immunity and Pathogenesis in
Experimental Human Metapneumovirus Infection. J Virol. 82:8560-8569.
Lai S., D. A. Stein,
A. Guerrero-Plata, S. Liao, C. Hong, P. L. Iversen, T.
Ivanciuc, A. Casola, and R. P. Garofalo.
(2008). Inhibition of Respiratory
Syncytial Virus
Infection
in Cell Cultures and in Mice with Morpholino Oligomers.
Mol Ther. 16:1120-1128.
Silva M.*, A. Guerrero-Plata*, F. Gilfoy, R. P. Garofalo and
P. Mason.
(2007). Differential Activation of Human Monocyte-derived and Plasmacytoid
Dendritic Cells by West Nile Virus Generated in Different Host Cells. J
Virol. 81:13640-13648. (*Equal contributors).
Castro S. M., A. Guerrero-Plata, G. Suarez-Real, P. A. Adegboyega, G.
N. Colasurdo, A. M. Khan, R. P. Garofalo and A. Casola.
(2006). Antioxidant Treatment Ameliorates RSV-induced Disease and Pulmonary
Inflammation. Amer J Respir Crit Care Med. 174:1361-1369.
Guerrero-Plata A.,
A. Casola, G. Suarez, X. Yu, L. Spetch, M. E. Peeples and R. P. Garofalo.
(2006). Differential Response of Dendritic Cells to Human Metapneumovirus
and Respiratory Syncytial Virus. Amer J Respir Cell Mol Biol. 34:
320-329.
Guerrero-Plata A.,
A. Casola and R. P. Garofalo.
(2005). Human Metapneumovirus Induces a Distinct Profile of Lung
Cytokines Compared to Respiratory Syncytial Virus. J Virol. 79:
14992-14997.
Guerrero-Plata A.,
S. Baron, J. Poast, P. A. Adegboyega, A. Casola and R. P. Garofalo.
(2005). Activity and Regulation of Alpha Interferon in Respiratory Syncytial
Virus and Human Metapneumovirus Experimental Infections. J Virol. 79:
10190-10199.
Guerrero-Plata A.,
E. Ortega, V. Ortiz-Navarrete and B. Gómez.
(2004). Antigen Presentation by a Macrophage-Like Cell Line Persistently
Infected with Respiratory Syncytial Virus. Virus Res. 99:95-100.
Guerrero-Plata A,
E. Ortega and B. Gómez.
(2001).
Persistence of Respiratory Syncytial Virus in Macrophages Alters
Phagocytosis and Proinflammatory Cytokines Production. Viral Immunol.
14:19-30.
Romero-Martinez R., M. Wheeler, A. Guerrero-Plata, G. Rico, and H. Torres-Guerrero.
(2000). Biosynthesis and Functions of Melanin in Sporothrix schenckii.
Infect Immun. 68:3696-703.
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