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Education:
B.S. Lucknow University, Lucknow, India M.S. Lucknow University
Ph.D. Lucknow University
Previous Positions
08/200712/2008
Post Doctoral Research Associate
Department of Pharmaceutical Sciences
Texas Tech University Health Sciences Center, Amarillo, Texas
FIELD OF STUDY:
Cancer & Inflammation, Chemoprevention
05/200607/2007
Post Doctoral Researcher
Davis Heart & Lung Research Institute, The Ohio State University, Columbus,
Columbus, Ohio, USA
FIELD OF STUDY:
Cancer & Inflammation, Chemoprevention
01/200201/2004
Post Doctoral Researcher (visiting scientist)
Department of Molecular & Cellular Biochemistry & Davis Heart & Lung
Research Institute, The Ohio State University, Columbus, Ohio, USA
02/199305/2006
Junior Biochemist
Department of
Biochemistry, Kalawati Saran Childrens Hospital, New Delhi, India
FIELD OF WORK: Routine Clinical Biochemistry, Special
Investigations, Supervision, Administration and Research
07/199001/1993
Senior Research
Fellow (Ph.D.)
Department of Biochemistry, Central Drug Research Institute, Lucknow, India
FIELD OF STUDY: Role and Metabolism of oxygen in
helminth parasites and their hosts
06/198707/1990
Junior Research
Fellow (For Ph.D.)
Department of Biochemistry, Central Drug Research Institute, Lucknow, India
Selected Publications:
Sahu, R.P., Zhang, R.,
Batra, S., Shi. Y. and Srivastava, S.K. (2009). Benzyl isothiocyanate
mediated generation of reactive oxygen species causes cell cycle arrest and
induces apoptosis via activation of MAPK in human pancreatic cancer cells.
Carcinogenesis, doi:10.1093/carcin/bgp157, June 23
Sahu, R.P.,
Batra, S. and Srivastava, S.K. (2009). Activation of ATM/Chk1 by
curcumin causes cell cycle arrest and apoptosis in human pancreatic cancer
cells. British Journal of Cancer 100, 1425 1433.
Nicholas, C.*,
Batra, S.*, Vargo, M.A. *, Voss, O.H., Gavrilin, M.A., Wewers, M.D.,
Guttridge, D., Grotewold, E., and Doseff, A.I. (2007). Apigenin blocks
lipopolysaccharide-induced lethality in vivo and proinflammatory cytokines
expression by inactivating NF-ĸB through the suppression of p65
phosphorylation. Journal of Immunology 179 (10), 7121-7127. [*Shared
First Authorship]
Voss, O.H. *,
Batra, S.*, Kolattukudy, S.J., and Doseff, A.I. (2007). Binding of
caspase-3 prodomain to heat shock protein 27 regulates monocyte apoptosis by
inhibiting caspase-3 proteolytic activation. Journal of Biological
Chemistry 282 (34), 25088-25099. [*Shared First Authorship]
Chandra, J., Jain,
V., Narayan, S., Sharma, S., Singh, V., Batra, S. and Dutta, A.K.
(2006). Tremors and thrombocytosis during treatment of megaloblastic anaemia.
Annals of Tropical Pediatrics 26(2), 101-105.
Huang, W., Batra,
S., Korrapati, S., Mishra, V., and Mehta, K.D. (2006). Selective
repression of low-density lipoprotein receptor expression by SP600125:
coupling of histone H3-ser10 phosphorylation and Sp1 occupancy. Molecular
and Cellular Biology, 26(4): 1307-1317.
Ojha, R.K., Singh,
S.K., Batra, S., Sreenivas, V. and Puliyel, J.M. (2006). Lactate:
creatinine ratio in babies with thin meconium staining of amniotic fluid.
BMC Pediatrics 6(13), 1-9.
Huang, W., Batra,
S., Atkins, B.A., Mishra, V., and Mehta, K.D. (2005). Increases in
intracellular calcium dephosphorylate histone H3 at Serine 10 in human
hepatoma cells: Potential role of protein phosphatase 2A-protein kinase CeII
complex. Journal of Cellular Physiology, 205(1): 37-46.
Huang, W., Mishra,
V., Batra, S., Dillon I., and Mehta, K.D. (2005). Phorbol ester
promotes histone H3-Ser10 phosphorylation at low density lipoprotein
receptor promoter in a protein kinase C-dependent manner in human hepatoma
HepG2 cells. Journal of Lipid Research, 45: 1519-1527.
Arora, P., Kumar,
V., Batra, S. (2002). Vitamin A status in children with asthma.
Pediatric Allergy and Immunology 13: 223-226.
Batra, S.#,
Kumar, R., Seema, A.K., Kapoor, A.K., Ray, G.N. (2000). Alterations in
antioxidant status during neonatal sepsis. Annals of Tropical Pediatrics
20: 27-33. [# Corresponding Author]
Ray, G.N., Aneja,
S., Jain, M., Batra, S.# (2000). Status of free radicals in childhood
meningitis. Annals of Tropical Pediatrics 20: 115-120. [
#Corresponding Author]
Ray, G.N., Batra,
S., Shukla, N.K., Deo, S., Raina, V., Ashok, S., Husain, S.A. (2000).
Lipid peroxidation, free radical production and antioxidant status in Breast
Cancer. Breast Cancer Research and Treatment 1586: 1-10.
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