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Education:
B.S. Lucknow University, Lucknow, India M.S. Lucknow University
Ph.D. Lucknow University
Previous Positions
08/200712/2008
Post Doctoral Research Associate
Department of Pharmaceutical Sciences
Texas Tech University Health Sciences Center, Amarillo, Texas
FIELD OF STUDY:
Cancer & Inflammation, Chemoprevention
05/200607/2007
Post Doctoral Researcher
Davis Heart & Lung Research Institute, The Ohio State University, Columbus,
Columbus, Ohio, USA
FIELD OF STUDY:
Cancer & Inflammation, Chemoprevention
01/200201/2004
Post Doctoral Researcher (visiting scientist)
Department of Molecular & Cellular Biochemistry & Davis Heart & Lung
Research Institute, The Ohio State University, Columbus, Ohio, USA
02/199305/2006
Junior Biochemist
Department of
Biochemistry, Kalawati Saran Childrens Hospital, New Delhi, India
FIELD OF WORK: Routine Clinical Biochemistry, Special
Investigations, Supervision, Administration and Research
07/199001/1993
Senior Research
Fellow (Ph.D.)
Department of Biochemistry, Central Drug Research Institute, Lucknow, India
FIELD OF STUDY: Role and Metabolism of oxygen in
helminth parasites and their hosts
06/198707/1990
Junior Research
Fellow (For Ph.D.)
Department of Biochemistry, Central Drug Research Institute, Lucknow, India
Selected Publications:
Wood, K.L., Voss, O.H., Huang, Q.,
Parihar, A., Mehta, N., Batra, S., Porcu, P. and Doseff, A.I. (2010).
The Small Heat Shock Protein 27 is a Key Regulator of CD8+CD57+ Lymphocyte
Survival. Journal of Immunology . doi:10.4049/jimmunol.0902953.
Cai , S., Batra, S., Sergio A.
Lira, Jay K. Kolls and Jeyaseelan S. (2010). CXCL1 Induced by IL-17
regulates NF-?B, MAP Kinases, CXCL2 and CXCL5 in the Lungs During
Klebsiella Pneumonia. Journal of Immunology. (In Press)
Batra,S., Ravi P. S., Khandala,
P.K. and Srivastava, S.K. (2010). Benzyl isothiocyanate mediated post
activation turn-off of NF-?B in pancreatic cancer cells leads to the onset
of apoptosis. Molecular Cancer Therapeutics. 1535-7163.MCT-09-1146;
Published OnlineFirst May 18, 2010.
Ravi P.S., Batra, S., Brown T.L.
and Srivastava, S.K. (2010). Mutation in K-Ras gene is associated with
resistance to TRAIL-induced apoptosis in pancreatic and lung cancer cell
lines. Cancer Chemotherapy and Pharmacology. (In Press)
Wood, K.L., Nunley, D.R., Bruce, S.M.,
Harman,A.P., Huang, Q., Shamo, E.N., Philips, G.S., Baran, C., Batra, S.,
Marsh, C.B. and Doseff, A.I. (2010). The Role of Heat Shock Protein 27 in
Bronchiolitis Obliterans Syndrome after Lung Transplantation. Journal of
Heart and Lung Transplantation. DOI: 10.1016/j.healun.2010.03.004
Balamayooran, G., Batra, S.,
Balamayooran, T., Cai*, S. and Jeyaseelan S. (2010). Mice lacking MCP-1 show
impaired neutrophil-mediated host defense in the lung against E. coli
. Journal of Immunology (In Revision)
Balamayooran, G., Batra, S.,
Fessler, M.B., Happel, K.H. and Jeeyaseelan, S. (2009). Mechanisms of
Neutrophil Accumulation in the Lungs Against Bacteria. (Translational
Review). American Journal of Respiratory Cell and Molecular Biology.
doi:10.1165/rcmb.2009-0047TR, September 8.
Cai , S., Batra, S., Shen, L.,
Wakamatsu, N., and Jeyaseelan S. (2009). Both TRIF-dependent and independent
signaling contribute to survival and bacterial clearance in Pulmonary
Klebsiella infection. Journal of Immunology. October 21, 2009,
doi:10.4049/jimmunol.0901033
Sahu, R.P., Zhang, R.,
Batra, S., Shi. Y. and Srivastava, S.K. (2009). Benzyl isothiocyanate
mediated generation of reactive oxygen species causes cell cycle arrest and
induces apoptosis via activation of MAPK in human pancreatic cancer cells.
Carcinogenesis, doi:10.1093/carcin/bgp157, June 23
Sahu, R.P.,
Batra, S. and Srivastava, S.K. (2009). Activation of ATM/Chk1 by
curcumin causes cell cycle arrest and apoptosis in human pancreatic cancer
cells. British Journal of Cancer 100, 1425 1433.
Nicholas, C.*,
Batra, S.*, Vargo, M.A. *, Voss, O.H., Gavrilin, M.A., Wewers, M.D.,
Guttridge, D., Grotewold, E., and Doseff, A.I. (2007). Apigenin blocks
lipopolysaccharide-induced lethality in vivo and proinflammatory cytokines
expression by inactivating NF-ĸB through the suppression of p65
phosphorylation. Journal of Immunology 179 (10), 7121-7127. [*Shared
First Authorship]
Voss, O.H. *,
Batra, S.*, Kolattukudy, S.J., and Doseff, A.I. (2007). Binding of
caspase-3 prodomain to heat shock protein 27 regulates monocyte apoptosis by
inhibiting caspase-3 proteolytic activation. Journal of Biological
Chemistry 282 (34), 25088-25099. [*Shared First Authorship]
Chandra, J., Jain,
V., Narayan, S., Sharma, S., Singh, V., Batra, S. and Dutta, A.K.
(2006). Tremors and thrombocytosis during treatment of megaloblastic anaemia.
Annals of Tropical Pediatrics 26(2), 101-105.
Huang, W., Batra,
S., Korrapati, S., Mishra, V., and Mehta, K.D. (2006). Selective
repression of low-density lipoprotein receptor expression by SP600125:
coupling of histone H3-ser10 phosphorylation and Sp1 occupancy. Molecular
and Cellular Biology, 26(4): 1307-1317.
Ojha, R.K., Singh,
S.K., Batra, S., Sreenivas, V. and Puliyel, J.M. (2006). Lactate:
creatinine ratio in babies with thin meconium staining of amniotic fluid.
BMC Pediatrics 6(13), 1-9.
Huang, W., Batra,
S., Atkins, B.A., Mishra, V., and Mehta, K.D. (2005). Increases in
intracellular calcium dephosphorylate histone H3 at Serine 10 in human
hepatoma cells: Potential role of protein phosphatase 2A-protein kinase CeII
complex. Journal of Cellular Physiology, 205(1): 37-46.
Huang, W., Mishra,
V., Batra, S., Dillon I., and Mehta, K.D. (2005). Phorbol ester
promotes histone H3-Ser10 phosphorylation at low density lipoprotein
receptor promoter in a protein kinase C-dependent manner in human hepatoma
HepG2 cells. Journal of Lipid Research, 45: 1519-1527.
Arora, P., Kumar,
V., Batra, S. (2002). Vitamin A status in children with asthma.
Pediatric Allergy and Immunology 13: 223-226.
Batra, S.#,
Kumar, R., Seema, A.K., Kapoor, A.K., Ray, G.N. (2000). Alterations in
antioxidant status during neonatal sepsis. Annals of Tropical Pediatrics
20: 27-33. [# Corresponding Author]
Ray, G.N., Aneja,
S., Jain, M., Batra, S.# (2000). Status of free radicals in childhood
meningitis. Annals of Tropical Pediatrics 20: 115-120. [
#Corresponding Author]
Ray, G.N., Batra,
S., Shukla, N.K., Deo, S., Raina, V., Ashok, S., Husain, S.A. (2000).
Lipid peroxidation, free radical production and antioxidant status in Breast
Cancer. Breast Cancer Research and Treatment 1586: 1-10.
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