Center Director - William G. Henk

Professor in the Department of Comparative Biomedical Sciences and Director of the School of Veterinary Medicine Microscopy Center

B.S., 1967, University of Georgia

M.Ed., 1971, University of Georgia

Ph.D., 1977, University of Georgia

Office - Rm 3429

Phone - (225) 578-9898

E-Mail

COLORADO

CHRISTMAS01

Instructional Activities:

Professional:

• VMED 5126 (Coordinator), Cell Biology and Histology
• VMED 5010 Cetacean Anatomy and Histology

Graduate:

• VAN 7112 Advanced Microscopic Anatomy
• 7105 Ultrastructural Cytology
• 7106 Electron Microscopy
• ZOOL 7800 Advanced Techniques in Light Microscopy.
  

Research:

As director of the Microscopy Center I become involved in many of the interesting research problems brought to the laboratory. This involvement may be in the form of consultation or it may be direct participation in the design and implementation of the investigation. My own funded research includes a long term investigation into various aspects of the morphology of the bowhead whale (Balaena mysticetus) and an investigation into the interactions of several small antimicrobial peptides with both prokaryotic and eukaryotic plasma membranes.

Recent Publications:

Zhu, Q., D.J. Hillmann, and W.G. Henk, 2001. The morphology the eye and surrounding structures of the bowhead whale, Balaena mysticetus. Mar. Mammal Sci. 17:729-750.

Catallo, J.W., C.H. Kennedy, W. Henk, S. Barker, S. Grace, and A. Penn, 2001. Combustion products of 1,3-butadiene are cytotoxic and genotoxic to human bronchial epithelial cells. Environ. Health Perspect. 109(9):965-971.

Penn, A., R. Nath, J. Pan, L.C. Chen, K. Widmer, W. Henk, and F.-L. Chung, 2001. 1,N2-Propanodeoxyguanosine adduct formation in aortic DNA following inhalation of acrolein. Environ. Health Perspect. 109(3):219-224.

Mutwiri, G.K., W.G. Henk, F.M. Enright, L.B. Borbeil, 2000. Effects of the antimicrobial peptide, D-Hecate on Trichomonads. J. Parasitol. 86:1355-1359.

Zhu, Q., D.J. Hillmann, and W.G. Henk, 2000. Observations on the muscles of the eye of the bowhead whale, Balaena mysticetus. Anat. Rec. 259:189-204.

Todd, C.W., E. Lee, M. Balusubramanian, H. Shah, W.G. Henk, L.E. Younger, and M.J. Newman, 1998, Systematic development of a block copolymer adjuvant for trivalent influenza virus vaccine. Dev. Biol. Stand. 92:341-351

Yu, K.H., P.S. Russo, L. Younger, W.G. Henk, D-H. Hua, G.R. Newkome, G. Baker, 1997. Observations on the thermoreversible gelation of two-directional arborol dendrimers in water-methanol mixtures. J. Polym. Sci.-Polym. Phys. 35:2787-2793.

Todd, C.W., L.-A. M. Pozzi, J.R. Guarnaccia, M. Balasubramanian, W.G. Henk, L.E. Younger, M.J.Newman, 1997. Rational design of adjuvant-active copolymers for use in subunit vaccines. Vaccine. 15(5):564-570.

Tarpley,R.J., D.J. Hillmann, W.G. Henk, J.C. George, 1997. Observations on the external morphology and vasculature of a fetal heart of the bowhead whale, Balaena mysticetus. Anat. Rec. 247:556-581.Hoskins, J.D., W.G. Henk, J. Storz, and M.T. Kearney, 1995. The potential use of a modified live FIPV vaccine to prevent experimental FECV infection. Feline Practice, 23(3):89-90.

Lo, W.C.J., W.G. Henk, and F.M. Enright, 1997. Light microscopic studies of 3T3 cell plasma membrane alterations mediated by melittin. Toxicon. 35(1):15-26.

Henk, W.G. and D.L. Mullan, 1996. Common epidermal lesions of the bowhead whale, Balaena mysticetus. Scanning Microsc. 10(3):905-916.

Catallo,W.J., W. Henk, L. Younger, O. Mills, D.J. Thiele, S.P. Meyers, 1996. Trace metal uptake by Pichia spartinae, and endosymbiotic yeast in the salt marsh cord grass Spartina alterniflora. Chemistry and Ecology. 13:113-131.

Henk, W.G., W.J. Todd, F.M. Enright, and PS Mitchell, 1995. The morphological effects of two anti-microbial lytic peptides, hecate-1 and melittin, on Escherichia coli. Scanning Microsc.9(2):501-507.

Research Associate - Olga Borkhsenious

M.S. 1967, Leningrad State University

Ph.D.1972, USSR Academy of Sciences, Leningrad

Olga is a senior microscopist with experience in operating and maintaining transmission, scanning electron microscopes, various light microscopes, and the other ancillary equipment of a centralized microscopy facility. She has considerable experience in various aspects of specimen preparation including extensive experience with immunolocalization. She regularly provides training and assistance to faculty, staff, and students in the preparation of samples and utilization of equipment. In addition, Olga teaches the laboratory portion of the graduate course (VAN 7106) in electron microscopy.

Specific Areas of Technical Expertise:

• Specimen preparation for SEM and TEM
• SEM & TEM operation and maintenance
• Immunogold localization - TEM
• Light Microscopy
• Photomicrography
• Photographic printing and layout for publication