Analytical Systems Lab

Research:

Analytical Toxicology and the Neurochemistry of Hallucinogens. Steven A. Barker, Ph.D., University of Alabama in Birmingham. Research into the adsorption, distribution, metabolism and clearance of hallucinogens, their mechanisms of action and their role as naturally occurring neurohormones. Studies are directed at characterization of neural pathways affected by hallucinogens and their related roles in the regulation of perception/cognition in health and disease. Research into the adsorption, distribution, metabolism and clearance of other drugs, particularly those that may effect the performance of racehorses, is also conducted.

Curriculum Vitae:

Recent Publications:

BARKER, S.A., 2005.Use of Matrix Solid-Phase Dispersion for Determining Pesticides in Fish and Foods, in Methods in Biotechnology: Analytical Protocols for Pesticide Analysis, Humana Press, M.E. Conti and F. Botre’, Editors; Chapter 22, pgs 285-296.

Arthur Penn, Gleeson Murphy, S.A. BARKER, William Henk and Lynn Penn, 2005, Combustion-Derived ultra-fine particles transport organic toxicants to target respiratory cells, Environmental Health Perspectives, 113, 956-963.

M. E. Myles, A. Azcuy, N. T. Nguyen, E. R. Reisch, S. A. BARKER, H. W. Thompson, and J. M. Hill, 2004, Bupropion (Zyban®, Wellbutrin®) inhibits nicotine-induced viral reactivation in HSV-1 latent rabbits. J. Pharmacol. & Exp. Ther., 311, 640-644.

Reiland, J., Sanderson, R.D., Waguespack, M., BARKER, S.A., Long, R., Carson, D.D., Marchetti ,D. , 2004, Heparanase degrades syndecan-1 and perlecan heparan sulfate: Functional implications for tumor cell invasion. J. Biol. Chem., 279, 8047-8055.

Myles, M.E., Alack, C. Manino, P.M., Reish, E.R., Higaki, S. Maruyama, K., Mallakin, A., Azcuy, A., BARKER, S.A., Ragan, F.A. and Hill, J.M., 2003, Nicotine applied by transdermal patch induces HSV-1 ocular shedding in latently infected rabbits. J. Ocular Pharmacol. & Ther., 19(2), 121-133.